19 May Why Estrogen?
Estrogen has over 400 functions in the body including: See Slides 17-19
Different Types of Estrogen and their function – Slide 20 – See Women’s BHRT Brochure middle panel on Estrogen
The term “Estrogen: actually refers to a group of related hormones, each with a unique profile of activity. Under normal circumstances, a woman circulating estrogen levels fluctuate based on her menstrual cycle. For Hormone Replacement Therapy, these hormones are often prescribed in combination to re-establish a normal physiologic balance. The three main estrogens produced in female humans are:
Estrone – E! (10-20% of circulating estrogens) is the primary estrogen produced after menopause
Estradiol – E2 – (10-30% of circulating estrogens) is the most potent and major secretory product of the ovary, and the predominant estrogen produced before menopause. Estradiol is the primary estrogen of ovarian origin and the major form of estrogen in pre-menopausal women.
Estriol -E3- (60-80% of circulating estrogens) is thought to be protective against breast cancer. Estriol has been shown to be clinically effective for the treatment of menopausal symptoms as well as postmenopausal problems including vaginal atrophy, dryness, vaginal infractions, painful intercourse, and various conditions of the urinary tract.
Use 1, 2 and 3 from attachment for specific benefits of Estrogen